During an experiment on the mice with (JAK) inhibitors. It was observed that the hair started growing in 3 weeks. With this positive sign, on trying it worked on human hair follicles too.
Janus Kinase (JAK) family of enzymes can settle into the roots. They have the strength to wake the dormant hair growing ingredients. It was this observation that gave a clear positive sign for further testing.
Dr Angela Christiano from Columbia University says it is a good discovery. But not yet for patterned baldness. She further says that more research and development needs to be done to make it more effective. they need to check whether it can induce hair growth when combined with a formulation for scalps or not.
The drug was an accidental discovery when Dr Angela Christiano and her team was studying alopecia areata, an autoimmune disease that causes hair loss.
On treating the mice with (JAK), they observed the hair started to grow within 10 days.
They then tested the drug on human hair follicles and surprisingly it showed the same effect.
Researchers are now keenly looking at its effect on hair follicles those are affected by hair loss disorders.